67 resources found

SAICM-USEtox_D8.1-Paper5-preprint
Academic article

Probabilistic reference and 10% effect concentrations for characterizing inhalation non-cancer and development/reproductive effects for 2,160 substances

Chemical management and risk assessment frameworks rely on regulatory toxicity values, but these are available for only a small fraction of commercialized chemicals due to limited available data. To address this gap, the study aims to expand the coverage of chemicals for which toxicity values can be derived by determining surrogate inhalation route points of departure (PODs) and corresponding toxicity values where regulatory assessments are lacking. In vivo data from the U.S. EPA's Toxicity Value Database were curated and selected, and effect values were adjusted to chronic human equivalent benchmark concentrations (BMCh) using the WHO/IPCS framework. Chemical-specific PODs are crucial for evaluating potential risks and toxicological impacts from chemical exposures, and the statistically derived BMCL or LOAEC/NOAEC are typically used as candidate PODs for toxicity value derivation.

This is a pre-print manuscript pending publication in open access scientific journals.

This document has been developed within the framework of the Global Environment Facility (GEF) project ID: 9771 on Global Best Practices on Emerging Chemical Policy Issues of Concern under the Strategic Approach to International Chemicals Management (SAICM).

Emerging Policy Issues: Chemicals in products
SAICM-USEtox_D8.1-Paper6-preprint
Academic article

Near-Field Exposures and Human Health Risks for Organic Chemicals in Interior Paints

The study examines the near-field exposures and health risks of organic chemicals in interior paints commonly used in Sri Lanka. The researchers developed mass balance-based and high-throughput models to predict chemical emissions during wet and dry phases and integrated these models into the USEtox model for health risk assessment. The models accurately predicted indoor air concentrations and drying time. They found that inhalation is the primary exposure pathway, and exposure is much higher for painters during application than for household members during use. The study identified chemicals of concern and recommended the use of protective equipment for painters and increasing air ventilation rates to reduce exposure for household members.

This is a pre-print manuscript pending publication in open access scientific journals.

This document has been developed within the framework of the Global Environment Facility (GEF) project ID: 9771 on Global Best Practices on Emerging Chemical Policy Issues of Concern under the Strategic Approach to International Chemicals Management (SAICM).

Emerging Policy Issues: Chemicals in products
Hinkley employees dismantling a laptop
Factsheets and brochures

Initiating Circularity for electronic waste in Nigeria: A promising paradigm for treating e-waste globally

Over half a million tonnes of discarded electronic appliances are improperly processed in Nigeria every year, threatening the country's environment and the health of approximately 100,000 informal workers in the recycling industry.
With support from the Global Environment Facility (GEF), the Government of Nigeria has joined forces with the United Nations Environment Programme (UNEP) and partners to turn the tide on e-waste under the “Circular Economy Approaches for the Electronics Sector in Nigeria” project. Led by UNEP and supported by the National Environmental Standards and Regulations Enforcement Agency of Nigeria (NESREA), the $15-million initiative brought together players from the Government, the private sector, and civil society to design and operationalise a financially self-sustaining circular economy (CE) for electronics in Nigeria.
The project aims to stimulate a CE pilot through an Extended Producer Responsibility (EPR) scheme that serves as a model for countries facing similar challenges. EPR is an integrated waste management approach that extends the responsibility of manufacturers to the entire lifecycle of their product, particularly to the end-of-life treatment. By applying this approach, the producers will be obliged to commission for collecting, pre-treating and recycling their originated e-waste. 
The project creates synergies among pre-existing elements of an EPR system in Nigeria to establish a sustainable management system and financing mechanism for EPR implementation. Establishing and enforcing a sustainable approach in Nigeria with supporting regulations and legally binding requirements is expected to recover and re-introduce usable materials into the value chain, dispose of hazardous e-waste streams in an environmentally sound manner, and create safe employment for Nigerian e-waste workers.
 

 

building-code-fact-sheet-19-01-23
Factsheets and brochures

Building Insulation Code Change Fact Sheet

In January 2019, the California Building Standards Commission unanimously approved changes to the state building codes proposed by the California Office of the State Fire Marshal. The changes allow use of polystyrene insulation without flame retardants below a concrete slab-on-grade. These changes would maintain fire safety while improving human and environmental health.  This fact sheet details the key considerations for implementation of a policy on allowing flame retardant-free insulation within a building code, and the associated health and technical considerations.

Emerging Policy Issues: Chemicals in products
Factsheets and brochures

Suggested Steps for Establishing a Lead Paint Law

December 2019
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This fact sheet outlines steps that have been helpful in countries that have adopted lead paint laws. The steps are not necessarily sequential or needed in every country.
Emerging Policy Issues: Lead in paint
Topics: Policymaking
Factsheets and brochures

Lead Paint Factsheet

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November 2019
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This factsheet presents the work of UNEP and the Lead Paint Alliance. The document also highlights its impacts and the SAICM GEF project Lead in paint component.
Emerging Policy Issues: Lead in paint
The Lancet
Academic article

Risk of cancer associated with residential exposure to asbestos insulation: a whole-population cohort study

November 2017
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The health risks associated with living in houses insulated with asbestos are unknown. Loose-fill asbestos was used to insulate some houses in the Australian Capital Territory (ACT). This study published in The Lancet compared the incidence of mesothelioma and other cancers in residents of the ACT who did and did not live in these houses.

Factsheets and brochures

The Potential Key Role of SAICM Focal Points in Reducing Harm from HHPs

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August 2022
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The factsheet entitled "The potential key role of SAICM Focal Points in reducing harm from Highly Hazardous Pesticides (HHPs)" was produced by stakeholders from the University of Cape Town, the Strategic Approach to International Chemicals Management, the Food and Agriculture Organization and Umweltbundesamt. This factsheet was developed to ensure information about HHPs reaches all SAICM National Focal Points and other relevant stakeholders for them to make effective and informed decisions and play an active role in facilitating the reduction of
Emerging Policy Issues: Highly Hazardous Pesticides
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