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The road map lays out actions and provides guidance on how to fully integrate gender in national chemicals management. These steps are meant to give support and direction to actors engaged in national chemicals management, especially SAICM National Focal Points. The accompanying workbook helps to prioritize and plan your activities step by step. Additionally, SAICM Focal Points and other stakeholders might be at different stages of capacity development, and priority actions and objectives will differ depending on the individual national context - the workbook, therefore, allows you to develop your specific process of integrating gender.

In this report, we present a list of Chemicals of Concern (CoCs) in plastic toys, with supporting information on the applied selection criteria. To identify the CoCs, we started from a literature review of available plastic toys compositions studies, and obtained the chemical mass fraction in plastic toy as well as the chemical functions. The chemical emissions from the plastic toys and subsequent human exposures were then estimated using a series of models and the coupled nearfield and far-field exposure assessment framework. Finally, the human exposure doses were compared to toxicity measures such as the reference dose (RfD), or median effective dose (ED50) for cancer effects, to evaluate the health risks on children. Chemical-material combinations that have a hazard quotient (HQ) > 10, a margin of exposure (MoE) < 100, or a lifetime cancer risk > 10-6 were included in the list of CoCs. In total, 35 (less than 10%) of all chemical-material combinations studied were identified as CoCs. The results indicate that a relevant amount of chemicals used in plastic toys may pose a non-negligible health risk to children, calling for more refined investigations and more human- and eco-friendly alternatives.

This document has been developed within the framework of the Global Environment Facility (GEF) project ID: 9771 on Global Best Practices on Emerging Chemical Policy Issues of Concern under the Strategic Approach to International Chemicals Management (SAICM). This project is funded by the GEF, implemented by UNEP and executed by the SAICM Secretariat.