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Endocrine-disrupting chemicals (EDCs) substantially cost society as a result of increases in disease and disability but—unlike other toxicant classes such as carcinogens—have yet to be codified into regulations as a hazard category.This Series paper examines economic, regulatory, and policy approaches to limit human EDC exposures and describes potential improvements. In the EU, general principles for EDCs call for minimisation of human exposure, identification as substances of very high concern, and ban on use in pesticides. In the USA, screening and

Lead is a toxic metal whose widespread use has caused extensive environmental contamination and health problems in many parts of the world. Human exposure to lead in 2017 was estimated to account for 1.06 million deaths and the loss of 24.4 million disability-adjusted-life-years (DALYs) from long-term health effects, with the highest burden falling on low- and middle-income countries.This document provides a brief overview of analytical methods available for measuring lead in paint. It is primarily aimed at informing public health

AbstractThe world faces an increasing need to phase out harmful chemicals and design sustainable alternatives across various consumer products and industrial applications. Alternatives assessment is an emerging field focusing on identifying viable solutions to substitute harmful chemicals. However, current methods fail to consider trade-offs from human and ecosystem exposures, and from impacts associated with chemical supply chains and product life cycles. To close this gap, we propose a life cycle based alternatives assessment (LCAA) framework for consistently integrating quantitative exposure

Microplastic contamination of the marine environment is widespread, but the extent to which the marine food web is contaminated is not yet known. The aims of this study were to go beyond visual identification techniques and develop and apply a simple seafood sample cleanup, extraction, and quantitative analysis method using pyrolysis gas chromatography mass spectrometry to improve the detection of plastic contamination.This method allows the identification and quantification of polystyrene, polyethylene, polyvinyl chloride, polypropylene, and poly (methyl methacrylate) in the

A guide for public interest organisations and policy-makersTo raise global awareness about endocrine-disrupting chemicals (EDCs) the Endocrine Society and IPEN have joined together to develop this EDC Guide. The guide draws from each organization’s strengths to present a more comprehensive picture of global EDC exposures and health risks than either could have done alone. Endocrine Society authors contributed the scientific and health-related content; IPEN provides knowledge of global policies and perspectives from developing and transition countries.

As there is an increase in communication of concrete recommendations for better solutions and alternatives to build a better economy that protects nature, there is an increased need to back these recommendations with facts and figures about how they contribute to reduce our impact on the planet.In this sense, the life cycle team has pulled together a very simple 2-page guidance on elements to consider when backing up your recommendations with strong life-cycle based science. The 2-pager also provides links

As the basis for managing the risks of chemical exposure, the Chemical Risk Assessment (CRA) process can impact a substantial part of the economy, the health of hundreds of millions of people, and the condition of the environment. However, the number of properly assessed chemicals falls short of societal needs due to a lack of experts for evaluation, interference of third party interests, and the sheer volume of potentially relevant information on the chemicals from disparate sources.In order to explore

Chemicals sector-specific information supplementing the manual when working with companies in this sector.