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Chemicals used in building materials can be a major passive emission source indoors, associated with the deterioration of indoor environmental quality. This study aims to screen the various chemicals used in building materials for potential near-field human exposures and related health risks, identifying chemicals and products of concern to inform risk reduction efforts. We propose a mass balance-based and high-throughput suited model for predicting chemical emissions from building materials considering indoor sorption. Using this model, we performed a screening-level human

AbstractBackgroundExisting models for estimating children’s exposure to chemicals through mouthing currently depends on the availability of chemical- and material-specific experimental migration rates, only covering a few dozen chemicals.ObjectiveThis study objective is hence to develop a mouthing exposure model to predict migration into saliva, mouthing exposure, and related health risk from a wide range of chemical-material combinations in children’s products.MethodsWe collected experimental data on chemical migration from different products into saliva for multiple substance groups and materials, identifying chemical concentration and