Estimating mouthing exposure to chemicals in children’s products

AbstractBackgroundExisting models for estimating children’s exposure to chemicals through mouthing currently depends on the availability of chemical- and material-specific experimental migration rates, only covering a few dozen chemicals.ObjectiveThis study objective is hence to develop a mouthing exposure model to predict migration into saliva, mouthing exposure, and related health risk from a wide range of chemical-material combinations in children’s products.MethodsWe collected experimental data on chemical migration from different products into saliva for multiple substance groups and materials, identifying chemical concentration and