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Reducing chemical pressure on human and environmental health is an integral part of the global sustainability agenda. Guidelines for deriving globally applicable, life cycle–based indicators are required to consistently quantify toxicity impacts from chemical emissions as well as from chemicals in consumer products. In response, we elaborate the methodological framework and present recommendations for advancing near-field/far-field exposure and toxicity characterization, and for implementing these recommendations into the scientific consensus model USEtox.The present work was supported by the “Global Best Practices

Since the global phase-out of leaded petrol, reports have suggested that lead exposure remains substantial or is increasing in some low-income and middle-income countries (LMICs). However, few studies have attempted to systematically assess blood lead levels over the full range of LMICs. This study is aimed to describe values for blood lead level in LMICs.In this systematic review, PubMed was searched for studies published between Jan 1, 2010, and Oct 31, 2019, that reported blood lead levels in the 137

On International Women’s Day, the Secretariat of the Minamata Convention on Mercury launched a video on how women are more negatively impacted by mercury and what needs to be done to better protect, support and promote gender equality. watch the videoThe Minamata Convention tackles mercury throughout its entire life cycle, fighting gender issues every step of the way. This includes supporting gender-specific trainings and helping implement National Action Plans with a gender perspective -- with special focus on the problem

SAICM Secretariat Team

We present a list of Chemicals of Concern (CoCs) in plastic toys. We started from available studies reporting chemical composition of toys to group plastic materials, as well as to gather mass fractions and function of chemicals in these materials. Chemical emissions from plastic toys and subsequent human exposures were then estimated using a series of models and a coupled near-field and far-field exposure assessment framework. Comparing human doses with reference doses shows high Hazard Quotients of up to 387

Video animation explaining why mercury and, in particular, mercury in skin lightening products is dangerous to health and the need for countries to take action to ban this source of exposure.

Environmental contamination with pharmaceuticals is widespread, inducing risks to both human health and the environment. This paper explores potential societal solutions to human and veterinary pharmaceuticals in the aquatic environment. To this end, we adopt transition research’s multi-level perspective framework, which allows us to understand the dynamics underlying pharmaceutical emissions and to recognize social and technical factors triggering change. The authors' qualitative analysis is based on data collected through literature research and interviews with actors from pharmaceutical industry, the health