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The video covers the crucial issues surrounding chemical policies in today's world, the unseen effects of chemicals in everyday life and the global push for policies that foster sustainable practices. The video highlights the challenges and innovative solutions that aim to to protect our environment and health, setting the stage for a greener, safer and sustainable future.

In this report, we present a list of Chemicals of Concern (CoCs) in plastic toys, with supporting information on the applied selection criteria. To identify the CoCs, we started from a literature review of available plastic toys compositions studies, and obtained the chemical mass fraction in plastic toy as well as the chemical functions. The chemical emissions from the plastic toys and subsequent human exposures were then estimated using a series of models and the coupled nearfield and far-field exposure assessment framework. Finally, the human exposure doses were compared to toxicity measures such as the reference dose (RfD), or median effective dose (ED50) for cancer effects, to evaluate the health risks on children. Chemical-material combinations that have a hazard quotient (HQ) > 10, a margin of exposure (MoE) < 100, or a lifetime cancer risk > 10-6 were included in the list of CoCs. In total, 35 (less than 10%) of all chemical-material combinations studied were identified as CoCs. The results indicate that a relevant amount of chemicals used in plastic toys may pose a non-negligible health risk to children, calling for more refined investigations and more human- and eco-friendly alternatives.

This document has been developed within the framework of the Global Environment Facility (GEF) project ID: 9771 on Global Best Practices on Emerging Chemical Policy Issues of Concern under the Strategic Approach to International Chemicals Management (SAICM). This project is funded by the GEF, implemented by UNEP and executed by the SAICM Secretariat.