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A company may choose to substitute a chemical to improve the safety or environmental footprint of a product or material.  In other cases, the primary reason may be to improve functionality, but it is important to ensure that substitute chemicals do not carry unintended health or pollution risks.  This guide form the European Chemicals Agency provides an overview of how to identify harmful substances and ensure that substitution practices are effective in improving safety and reducing chemical impacts.

OECD have compiled a range of frameworks, guides and toolkits are available to support sound chemical substitution processes.

A guide from ChemSec aiming to simplify the process of chemical substitution

This guide is produced by the RISE Research Institutes of Sweden.The substitution guide is aimed for all businesses who want to start working on systematic chemical work. It might be best suited for small and medium-sized companies that are just starting their work. The guide does not address any specific industry, but the examples and templates are developed for producing companies and companies that work with trade in goods.

The substitution guide provides practical advice and recommends tools and resources that are relevant to the goal of each step. Some resources can be used in several steps, so they are mentioned several times so that you know how the resources are intended to be used.

The Portal provides information to supporting efforts in substituting hazardous substances and assisting in finding safer alternatives. 

Per- and polyfluoroalkyl substances (PFAS) are a large class of thousands of synthetic chemicals that are used throughout society. However, they are increasingly detected as environmental pollutants and some are linked to negative effects on human health.

This page from the European Chemicals Agency provides background on PFAS chemicals and their use in a number of products, including construction materials, paints and chrome plating.

On 13th January 2023, the European Commission issued a proposal that would ban the manufacture and use of PFAS chemicals, including those used in building materials. 

The details of the proposed restriction of around 10,000 per- and polyfluoroalkyl substances (PFASs) are now available on ECHA’s website. ECHA’s scientific committees have begun to evaluate the proposal in terms of the risks to people and the environment, and the impacts on society, in accordance with the below timeline.  A six-month consultation began in March 2023 and will close on 25 September 2023.

Document: Consultation on a proposed restriction on the manufacture, placing on the market and use of per- and polyfluoroalkyl substances (PFAS)