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AbstractThe world faces an increasing need to phase out harmful chemicals and design sustainable alternatives across various consumer products and industrial applications. Alternatives assessment is an emerging field focusing on identifying viable solutions to substitute harmful chemicals. However, current methods fail to consider trade-offs from human and ecosystem exposures, and from impacts associated with chemical supply chains and product life cycles. To close this gap, we propose a life cycle based alternatives assessment (LCAA) framework for consistently integrating quantitative exposure

Endocrine-disrupting chemicals (EDCs) substantially cost society as a result of increases in disease and disability but—unlike other toxicant classes such as carcinogens—have yet to be codified into regulations as a hazard category.This Series paper examines economic, regulatory, and policy approaches to limit human EDC exposures and describes potential improvements. In the EU, general principles for EDCs call for minimisation of human exposure, identification as substances of very high concern, and ban on use in pesticides. In the USA, screening and

Plastics are used across the economy and in diverse downstream sectors such as packaging, construction, transportation, healthcare, textiles, and electronics. Durable products, ranging from construction materials to medical devices make up nearly half of the global plastics market, while packaging products are the largest uses of single-use plastics. Some plastics contain chemicals that are considered to be harmful for health and the environment. Phthalates, poly-fluorinated chemicals, bisphenol A (BPA), brominated flame retardants and antimony trioxide are considered most harmful for

This document has been developed for officials in government who have a role in regulating lead paint, to provide them with concise technical information on the rationale and steps required to phase out lead paint. “Lead paint” or “lead-based paint” is paint to which one or more lead compounds have been intentionally added by the manufacturer to obtain specific characteristics. This document explains the health and economic importance of preventing lead exposure by establishing legally binding controls to stop the

Lead has toxic effects on almost all body systems and is especially harmful for children and pregnant women. Lead paint is an avoidable source of exposure to lead. “Lead paint” or “lead-based paint” is paint to which one or more lead compounds have been intentionally added by the manufacturer to obtain specific characteristics. One important way to prevent exposure is for countries to establish legally binding regulatory measures prohibiting the addition of lead to paint.This policy brief summarizes key information

Medicinal products are physiologically highly active substances that enter the water and soil, particularly through human and animal excretion. They are being detected in the environment to a greater and greater extent, often in concentrations that are not harmless to humans and other living organisms. The consumption of pharmaceuticals is increasing, mainly due to the aging of the population. Consequently, measures to reduce environmental pollution are therefore necessary.

The OECD releases the Revised Guidance Document 150 on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals. The document is intended to provide guidance for evaluating chemical using standardised test guidelines. Specific objectives include providing a description of the OECD conceptual framework

The GGKP is a global community of organisations and experts committed to collaboratively generating, managing and sharing green growth knowledge and data to mobilise a sustainable future.

Website of SETAC, Society of Environmental Toxicology and ChemistrySETAC is a not-for-profit, worldwide professional organization composed of more than 5,300 individuals and institutions in over 90 countries dedicated to the study, analysis and solution of environmental problems, the management and regulation of natural resources, research and development and environmental education. SETAC’s mission is to support the development of principles and practices for protection, enhancement and management of sustainable environmental quality and ecosystem integrity.

The Building Circularity Platform provides an understanding of the circularity concept, its scope and how it contributes to promoting sustainable consumption and production patterns. It also offers a wide range of resources and features stories illustrating how various stakeholders have successfully adopted circular approaches.