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Endocrine-disrupting chemicals (EDCs) substantially cost society as a result of increases in disease and disability but—unlike other toxicant classes such as carcinogens—have yet to be codified into regulations as a hazard category.This Series paper examines economic, regulatory, and policy approaches to limit human EDC exposures and describes potential improvements. In the EU, general principles for EDCs call for minimisation of human exposure, identification as substances of very high concern, and ban on use in pesticides. In the USA, screening and

This WHO policy brief presents the consequences of lead exposure on human health and details its toxicity in the body system explaining why it is important to reduce the use and releases of lead, and to reduce environmental and occupational exposures, particularly for children and women of childbearing age.The policy brief also lists the sources of lead releases and contamination in industrial process, drinking water and domestic sources. The brief also gives guidelines for tolerable intake levels of lead and

Since the global phase-out of leaded petrol, reports have suggested that lead exposure remains substantial or is increasing in some low-income and middle-income countries (LMICs). However, few studies have attempted to systematically assess blood lead levels over the full range of LMICs. This study is aimed to describe values for blood lead level in LMICs.In this systematic review, PubMed was searched for studies published between Jan 1, 2010, and Oct 31, 2019, that reported blood lead levels in the 137

Over the past decade a great amount of interest has arisen regarding the occurrence and fate of trace organic contaminants in the aquatic environment. Of particular concern are human hormones and pharmaceuticals, many of which are ubiquitous contaminants in conventional municipal wastewater treatment plant effluents when measured with ng/L detection limits. As analytical procedures and bioassay techniques become more readily available and increasingly sensitive, new contaminants will be discovered. The presence or absence of any chemical in a wastewater effluent

Endocrine disrupting compounds (EDCs) and pharmaceuticals and personal care products (PPCPs) are a group of chemical compounds with diverse physical and chemical properties. Recent studies have indicated undesired effects of EDCs and PPCPs at their reported trace concentrations. This paper reviews the current knowledge on the sources, properties, occurrence and health impacts of EDCs and PPCPs, and their removal from drinking water using ozonation and ozone/hydrogen peroxide-based advanced oxidation. The paper also examines the potential threats posed by these chemicals