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Chemicals of concern (CoCs) contained in everyday products can have harmful impacts on human health and the environment. While chemical-related impacts can often occur during a product’s use or end-of-life, decisions influencing product ingredients are taken further upstream of the value chain. Action to address CoCs in products thus need to consider the entire value chain and impactful interventions need to be made at upstream stages to protect human health and the environment from chemical pollution. UNEP is working on

We present a list of Chemicals of Concern (CoCs) in plastic toys. We started from available studies reporting chemical composition of toys to group plastic materials, as well as to gather mass fractions and function of chemicals in these materials. Chemical emissions from plastic toys and subsequent human exposures were then estimated using a series of models and a coupled near-field and far-field exposure assessment framework. Comparing human doses with reference doses shows high Hazard Quotients of up to 387

AbstractThe world faces an increasing need to phase out harmful chemicals and design sustainable alternatives across various consumer products and industrial applications. Alternatives assessment is an emerging field focusing on identifying viable solutions to substitute harmful chemicals. However, current methods fail to consider trade-offs from human and ecosystem exposures, and from impacts associated with chemical supply chains and product life cycles. To close this gap, we propose a life cycle based alternatives assessment (LCAA) framework for consistently integrating quantitative exposure