This WHO technical report focuses on reviewing the risks to human health associated with exposure to trace concentrations of pharmaceuticals in drinking-water. Pharmaceuticals are synthetic or natural chemicals that can be found in prescription medicines, over-the-counter therapeutic drugs and veterinary drugs. Pharmaceuticals contain active ingredients that have been designed to have pharmacological effects and confer significant benefits to society. Traces of pharmaceuticals, typically at levels in the nanograms to low micrograms per litre range, have been reported in the water